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You might have heard of insulin in
connection with the disease known as diabetes. Still, you might be
curious about insulin—what it means for the body and what can happen
if the body does not produce enough of it. In addition, chances are
you know little about the history of insulin and how science’s
knowledge of insulin has changed over the years.
To begin with, knowledge about
insulin is a relatively new phenomenon. Berlin medical student Paul
Langerhans first discovered insulin in 1869. Using a microscope,
Langerhans noticed a heap of cells in the pancreas which later
became known as the Islets of Langerhans. Later, scientists surmised
that these cells produce insulin, which regulates carbohydrate
metabolism. In January of 1922, Leonard Thompson, a 14-year-old
diabetic, received the first insulin injection. Because the extract
was impure, Thompson experienced a severe allergic reaction. As a
result, doctors cancelled future insulin injections for Thompson.
However, in later years, researchers were able to perfect insulin
injections, making them the primary means of treating diabetes.
In addition to its role in metabolism, insulin controls the storage
and release of fat, the cellular uptake of amino acids and
electrolytes, and affects small vessel muscle tone. In fact, the
concentration of insulin can affect the entire body. This is why
diabetics can suffer a variety of side-effects, including blindness
and slow healing of wounds. Those who suffer from type 1 diabetes
require insulin injections in order to survive, while type 2
diabetes patients may need insulin if other medication and dietary
changes are ineffective in controlling blood glucose levels.
At this point, it is not possible to take insulin orally. Instead,
insulin is administered through syringes with needles, or insulin
pens with needles. However, there are a number of problems
associated with insulin as a treatment for diabetes. For instance,
it can be difficult to determine the appropriate dose of insulin.
The dosage, as well as the timing of the dosage, must often be
adjusted, based upon eating habits, exercise routines, or the
additional stress of illness. Insulin injections can be a nuisance
for patients and, if the patient makes a mistake in terms of dosage,
they can actually be dangerous.
Still, when it is used appropriately,
insulin can help restore the body’s metabolism to normal levels. As
a result, through proper administration of insulin, athletes and
artists can perform at their optimal level without difficulty. For
instance, Olympic swimmer Gary Hall Jr. is an example of a diabetic
who has been helped by insulin, while David Crosby of the singing
group Crosby, Stills & Nash has also benefited from insulin
injections.
In the year 2004, the former spouse
of an international track star maintained that the athlete had used
insulin to energize the body. The report promoted the idea that the
hormone insulin could be utilized like a steroid in enhancing the
body’s functions. However, researchers say that insulin does not
have the same effects as steroids. They say that eight decades of
steroid use do not indicate that insulin could be used as a
performance-enhancing drug for those who are not diabetics. While
insulin can help to alleviate fatigue for those with diabetes, it
does not have the same chemical composition as a steroid. Therefore,
doctors say that the use of insulin by non-diabetics is, in fact,
dangerous.
Proper use of insulin is essential
for those with type 1 diabetes. It can enable them to lead a normal,
productive life. However, while insulin is a legitimate treatment
for diabetes, it is not a cure. Research is now underway to try to
make diabetes a disease of the past and to make insulin injections
unnecessary.
Ray Kelly is
an Exercise Scientist with 15 years experience in the health and
fitness industry. Sign up for his Free Exercise and Meal Planner at
The Biggest Loser
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